| Absztrakt (kivonat): |
To survive and reproduce, a cell must process information from its environment and its own internal state and respond accordingly, in terms of metabolic activity, gene expression, movement, growth, division and differentiation. These signal-response decisions are made by complex networks of interacting genes and proteins, which function as biochemical switches and clocks, and other recognizable information-processing circuitry. This theme issue of Interface Focus (in two parts) brings together articles on time-keeping and decision-making in living cells-work that uses precise mathematical modelling of underlying molecular regulatory networks to understand important features of cell physiology. Part I focuses on time-keeping: mechanisms and dynamics of biological oscillators and modes of synchronization and entrainment of oscillators, with special attention to circadian clocks. |
| További információ: |
Department of Biological Sciences, Virginia Polytechnic Institute, State University, Blacksburg, VA 24061, United States
Faculty of Information Technology and Bionics, Pázmány Péter Catholic University, Budapest, 1088, Hungary
Unit of Theoretical Chronobiology, Université Libre de Bruxelles, Brussels, 1050, Belgium
Department of Mathematical Sciences, KAIST, Daejeon, 34141, South Korea
Biomedical Mathematics Group, Institute for Basic Science, Daejeon, 34126, South Korea
Quantitative Stem Cell Biology Laboratory, The Francis Crick Institute, London, NW1 1AT, United Kingdom
Mathematical Modeling of Cellular Processes, Max Delbrück Center for Molecular Medicine, Berlin, 13125, Germany
Department of Mathematics and Computer Science, Free University, Berlin, 14195, Germany
Cited By :1
Export Date: 4 April 2023
Correspondence Address: Tyson, J.J.; Department of Biological Sciences, United States; email: tyson@vt.edu |
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