Time-keeping and decision-making in living cells: Part I

Tyson John J. and Csikász-Nagy Attila and Gonze Didier and Kim Jae Kyoung and Santos Silvia and Wolf Jana: Time-keeping and decision-making in living cells: Part I.
INTERFACE FOCUS, 12 (3). ISSN 2042-8898 (2022)

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Item Type:

Article

Creators:

Creators	ORCID	MTMT szerző azonosító
Tyson John J.
Csikász-Nagy Attila	0000-0002-2919-5601	10012379
Gonze Didier
Kim Jae Kyoung	0000-0001-7842-2172
Santos Silvia
Wolf Jana

Abstract:

To survive and reproduce, a cell must process information from its environment and its own internal state and respond accordingly, in terms of metabolic activity, gene expression, movement, growth, division and differentiation. These signal-response decisions are made by complex networks of interacting genes and proteins, which function as biochemical switches and clocks, and other recognizable information-processing circuitry. This theme issue of Interface Focus (in two parts) brings together articles on time-keeping and decision-making in living cells-work that uses precise mathematical modelling of underlying molecular regulatory networks to understand important features of cell physiology. Part I focuses on time-keeping: mechanisms and dynamics of biological oscillators and modes of synchronization and entrainment of oscillators, with special attention to circadian clocks.

Journal or Publication Title:

INTERFACE FOCUS

Date:

2022

Volume:

Number:

ISSN:

2042-8898

Institution:

Pázmány Péter Katolikus Egyetem

Kar:

Információs Technológiai és Bionikai Kar (2013.07.-)